Liverpool will attempt to sweep away the January blues on the last day of a wretched month when they host commanding Premier League leaders Chelsea at Anfield on Tuesday.
Successive home defeats by leaders Leicester City and second placed Tottenham Hotspur have left City six points off the pace with serious doubts about whether their expensively-assembled squad is still playing for the manager.
'Before the start of the season I felt Manchester United will be a lot better this year and they were my tip for the title'
A trip to Manchester United has in the past struck fear into the heart of many an opposition team, but that will not apply to Chelsea on Sunday because they know history is on their side.
Champions Chelsea have not enjoyed the best of starts at home this season and face their biggest test yet on Saturday with the visit of free-scoring leaders Manchester City.
A round-up of Saturday's action in the Premier League.
Barcelona goalkeeper Marc-Andre ter Stegen is wary of the danger posed by Juventus forward Paulo Dybala ahead of their opening Champions League Group D clash on Tuesday.
Tottenham Hotspur have shown impressive durability in the Premier League lately, but they will need to be at their most steadfast to deny champions and league leaders Manchester City who travel to Wembley on Monday.
The 30-year-old joins Luke Shaw in the treatment room after the left back pulled out of the England squad with an injury on Monday.
Chelsea striker Tammy Abraham scored a late opportunist double to secure a 3-0 home win for Chelsea over West Ham United in the English Premier League on Monday.
A stunning free kick from Willian seven minutes from time gave Chelsea a nervy and hard-fought 2-1 UEFA Champions League Group G win over Dynamo Kiev on Wednesday to lift some of the gloom surrounding Stamford Bridge.
Liverpool manager Juergen Klopp acknowledged that they would have to defend better in the visit to Stamford Bridge to stop Eden Hazard reprising the sort of solo brilliance that propelled Chelsea to victory at Anfield on Wednesday.
Images from Saturday's action in the Premier League.
On the face of it, Jose Mourinho shouldered the blame for the wounding defeat in his first Manchester derby at Old Trafford on Saturday.
Chelsea begin their Premier League title defence against Swansea City on Saturday in the unusual position of heading into a new season having been significantly outspent by their rivals.
The Community Shield showpiece at Wembley will be the 14th time Arsene Wenger and Jose Mourinho have locked horns in opposing dugouts and Wenger is still waiting to get one over the Portuguese.
Chelsea manager Jose Mourinho has hit out at the Premier League schedule, saying his players have not had a chance to recover from their midweek Champions League match before playing Fulham on Saturday.
IMAGES from the English Premier League matches played on Saturday.
Departing captain John Terry led his Chelsea champions to a rip-roaring 4-3 victory over Watford on Monday, scoring the first goal on an evening of celebration, fireworks and streamers rather than vintage football at Stamford Bridge.
The victory, Chelsea's 28th of the season, put the long-time league leaders 10 points clear of second-placed Tottenham Hotspur, who have only three games left to play.
Manchester United captain Nemanja Vidic will leave the Premier League club at the end of the season, flagging a move abroad and signalling a possible break-up of Alex Ferguson's last great team at Old Trafford.
Nuggets of news coming from the English Premier League
Inspirational manager Juergen Klopp has rekindled the Anfield flame though and delivered the club's 19th top-flight title, one behind arch-rivals United's record of 20, after finishing runners-up to City in a thrilling race last season.
Arsenal striker Lukas Podolski scored twice in the opening half-hour as the Premier League leaders romped to a 4-0 win over third-tier Coventry City in their FA Cup fourth round tie at the Emirates on Friday.
News of all that's transpired on and off the football field
Antonio Conte bowed out as Italy coach on Saturday after a Euro 2016 shootout defeat by Germany sounding almost broken-hearted that he was leaving behind a "fantastic" group of players.
Liverpool manager Brendan Rodgers was left casting envious glances at his rivals' squads after a second defeat in four days bruised their title challenge and left him looking up the table rather than down.
Jose Mourinho has won a trophy every season of his top flight career and finds it "unacceptable" to contemplate finishing his comeback season with Chelsea empty handed.
Images from Monday's action in the Premier League.
Leicester City failed to grasp their first chance to clinch the Premier League title when they drew 1-1 at Manchester United on Sunday but they moved ever closer to a first English top-flight crown.
News of all that's transpired on and off the football field
Arsenal travel across town to a vengeful Chelsea on Saturday knowing that another depressing defeat at Stamford Bridge would see their Premier League title hopes swept away with the lunchtime leftovers.
Following Bayern Munich's brilliant 7-4 (on aggregate) win over FC Porto in the quarter-finals of the Champions League, here's a look at a few memorable come-from-behind victories in Europe's premier football competition.
Cristiano Ronaldo hit back at critical former boss Jose Mourinho in the best way possible on Wednesday with two goals to help Real Madrid beat Chelsea 3-1 and win the International Champions Cup pre-season tournament.
Raheem Sterling's stunning individual goal earned Liverpool a 1-1 draw with Chelsea in a rip-roaring League Cup semi-final first leg at Anfield on Tuesday but the dominant Merseysiders could be left to rue a missed opportunity.
Chelsea may have restored some breathing space over Manchester City with a 2-0 win over Newcastle United on Saturday but they have not regained the form that made them runaway title favourites earlier in the season.
Images from the English Premier League matches played on Saturday.
Paris St Germain substitute Edinson Cavani, criticised by French media lacking composure in front of goal, responded in style to earn a 2-1 home win over Chelsea in their Champions League last-16 first leg on Tuesday.
IMAGES from the EPL matches played on Wednesday
With dreams of European glory in tatters, Manchester United, Chelsea and Tottenham Hotspur turn their attention to the FA Cup quarter-finals this weekend clinging to their last chance of silverware this season.